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5
The intraday and interday analytical accuracies and
variability are presented in Tables 4 and 5, respectively.
For each analyte, intraday variability and accuracy were
determined by analyzing five samples at each QC level.
For interday variability and accuracy, the process
performed for intraday data was repeated on three
different days. For the intraday study, the accuracy
obtained was between 94% and 112% with a %RSD
less than 12%. In the case of interday assays, the accuracy
was between 93% and 111% with a %RSD less than
13%. The obtained results show a low variability for the
two QC levels as well as good accuracy.
Figure 2. Chromatograms of the SRM transitions of some commonly found benzodiazepines at the LOQ