 
          Differentiate Minor Difference of Protein
        
        
          Structure in Biosimilar and Reference Products
        
        
          Using High-Resolution Orbitrap LC-MS/MS
        
        
          
            Zhiqi Hao,
          
        
        
          
            1
          
        
        
          
            David M. Horn,
          
        
        
          
            1
          
        
        
          
            Shiaw-Lin Wu,
          
        
        
          
            2
          
        
        
          
            Fan Zhang,
          
        
        
          
            2
          
        
        
          
            and Patrick Bennett
          
        
        
          
            1
          
        
        
          
            1
          
        
        
          
            Thermo Fisher Scientific, San Jose, CA;
          
        
        
          
            2
          
        
        
          
            Barnett Institute, Northeastern University, Boston, MA