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6

Figure 6. Extracted ion chromatogram from donor sample obtained in confirmation PRM experiment.

Codeine in Donor D2, 12.1 ng/mL

Hydrocodone in Donor F1, 60.6 ng/mL

Hydromorphone in Donor D3, 37.1 ng/mL

Morphine in donor F3, 217 ng/mL

Oxycodone in Donor D1, 4.38 ng/mL

Oxymorphone in Donor M2, 698 ng/mL