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Application Note 52295
Conclusion
The ISQ
™
single quadrupole GC-MS system utilizing the
TriPlus
™
RSH autosampler and a PTV inlet (CT-Splitless
mode) demonstrated its capability to analyze 1,4-dioxane
according to EPA Method 522. It easily met the criteria
for tuning with BFB and for calibration down to a level of
0.05 ppb. For better accuracy at the lower end of the
curve, 1/x weighting was used to meet all of the criteria of
the initial calibration of EPA Method 522. SIM analysis
gave excellent results at low concentrations. The added
advantage of the SIM/Full Scan mode is the ability to
identify unknowns with a NIST or other library, while
producing accurate results for 1,4-dioxane.
References
1) International Chemical Safety Card: 1,4-Dioxane.
National Institute for Occupational Safety and Health.
http://www.cdc.gov/niosh/ipcsneng/neng0041.html.Retrieved 15 May 2012.
2
)http://www.organicconsumers.org/bodycare/DioxaneRelease08.cfm
3) “1, 4-Dioxane Fact Sheet: Support Document”. OPPT
Chemical Fact Sheets. United States Environmental
Protection Agency. February
1995
.
4)EPA/600/R-08/101, Method 522 Determination of
1,4-Dioxane in Drinking Water by Solid Phase
Extraction (SPE) and Gas Chromatography/Mass
Spectrometry (GC/MS) with Selected Ion Monitoring
(SIM), Version 1.0, September,
2008
, Jean W. Munch
and Paul E. Grimmett.
AN52295_E 06/12C
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