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The ion exchange properties have a major impact on the shape of the radar plots, and this allows for a separation of the
HILIC stationary phases into two main groups:
Group 1: For phases which have little ion-exchange activity. These materials can be used for neutral, zwitterionic
and mixtures of acids and bases.
Group 2: For phases which have considerable ion-exchange activity. Group 2 can be divided further in two
subcategories:
a) Anion exchange phases; recommended for the analysis of acids.
b) Cation exchange phases; recommended for the analysis of bases.
Group 1 – Radar plots for HILIC stationary phases with no ion-exchange properties
Group 2a – Radar plot for HILIC stationary phase with anion exchange properties
Syncronis HILIC
(Tb/Tp)
(2dG/3dG)
k U /2
(CX) /2
(OH)
(V/A)
(AX)
(CH2)
Accucore
150-Amide-HILIC
(Tb/Tp)
(2dG/3dG)
k U /2
(CX) /2
(OH)
(V/A)
(AX)
(CH2)
Accucore Urea-HILIC
(Tb/Tp)
(2dG/3dG)
k U /2
(CX) /2
(OH)
(V/A)
(AX)
(CH2)
Acclaim HILIC-10
(Tb/Tp)
(2dG/3dG)
k U /2
(CX) /2
(OH)
(V/A)
(AX)
(CH2)
Hypersil GOLD HILIC
(Tb/Tp)
(2dG/3dG)
k U /2
(CX) /2
(OH)
(V/A)
(AX)
(CH2)
