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Affinity chromatography is based on

the biospecific interaction between a

biomolecule and its ligand. This interaction is

reversible and therefore specific compounds

can be isolated from complex matrices such

as cell culture used for mAb production.

By doing this, the concentration, or titer,

of a biotherapeutic protein during the

manufacturing process can be determined.

Affinity titer is an extremely important

technique in the biopharmaceutical industry

as it is used during several stages of the

biotechnological protein production process.

Titer (Affinity)

Recommended Column

Thermo Scientific

MAbPac Protein A 12 µm,

4.0

×

35 mm column

Product code: 082539

• Full titer analysis in less than 2 minutes

• Linearity over a sample concentration

range of 0.025 to 5mg/mL

Sample Preparation

SOLAµ SPE Plates

for

increased sensitivity

Sample Handling

Virtuoso Vials

The highest level of sample

integrity and sample

information possible

Column

MAbPac Protein A Columns

UHPLC

Vanquish UHPLC Systems

Built for every

biopharma workflow