Affinity chromatography is based on
the biospecific interaction between a
biomolecule and its ligand. This interaction is
reversible and therefore specific compounds
can be isolated from complex matrices such
as cell culture used for mAb production.
By doing this, the concentration, or titer,
of a biotherapeutic protein during the
manufacturing process can be determined.
Affinity titer is an extremely important
technique in the biopharmaceutical industry
as it is used during several stages of the
biotechnological protein production process.
Titer (Affinity)
Recommended Column
Thermo Scientific
™
MAbPac ™ Protein A 12 µm,4.0
×
35 mm column
Product code: 082539
• Full titer analysis in less than 2 minutes
• Linearity over a sample concentration
range of 0.025 to 5mg/mL
Sample Preparation
SOLAµ SPE Platesfor
increased sensitivity
Sample Handling
Virtuoso VialsThe highest level of sample
integrity and sample
information possible
Column
MAbPac Protein A ColumnsUHPLC
Vanquish UHPLC SystemsBuilt for every
biopharma workflow