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Antibodies are becoming increasingly

important in the development and

manufacture of drugs globally. During the

manufacturing process, antibodies and

other proteins can form aggregates – these

occur when several structures join together

to form larger, higher order structures. This

can impact the efficacy of a drug, which

ultimately can lead to severe side-effects

for the consumer. Biopharmaceutical

companies therefore have a requirement

to accurately measure this aggregation to

ensure that levels are minimized.

Recommended Column

Thermo Scientific

MAbPac SEC-1 5 µm,

7.8 x 300 mm column

Product code: 088460

• Features a proprietary hydrophilic bonded

layer, designed to minimize the interactions

between the biomolecules of interest and

the stationary phase

• Provide accurate quantification of

aggregation level within the drug

• Confirmation of drug safety within

regulatory requirements

Aggregation

Sample Preparation

Thermo Scientific

SOLAµ SPE Plates

for increased sensitivity

Sample Handling

Thermo Scientific

Virtuoso Vials

The highest level of sample integrity

and sample information possible

Column

MAbPac SEC-1 BioLC Columns

UHPLC

Thermo Scientific

Vanquish UHPLC Systems

Built for every biopharma workflow