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Antibodies are becoming increasingly

important in the development and

manufacture of drugs globally. During the

manufacturing process, antibodies and

other proteins can form aggregates – these

occur when several structures join together

to form larger, higher order structures. This

can impact the efficacy of a drug, which

ultimately can lead to severe side-effects

for the consumer. Biopharmaceutical

companies therefore have a requirement

to accurately measure this aggregation to

ensure that levels are minimized.

Recommended Column

Thermo Scientific

™

MAbPac ™ SEC-1 5 µm,

7.8 x 300 mm column

Product code: 088460

• Features a proprietary hydrophilic bonded

layer, designed to minimize the interactions

between the biomolecules of interest and

the stationary phase

• Provide accurate quantification of

aggregation level within the drug

• Confirmation of drug safety within

regulatory requirements

Aggregation

Sample Preparation

Thermo Scientific

™

SOLAµ ™ SPE Plates

for increased sensitivity

Sample Handling

Thermo Scientific

™ Virtuoso ™ Vials

The highest level of sample integrity

and sample information possible

Column

MAbPac SEC-1 BioLC Columns

UHPLC

Thermo Scientific

™

Vanquish ™ UHPLC Systems

Built for every biopharma workflow