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Thermo Scientific Poster Note
•
PN64227-MSACL-EN 0814S
Conclusion
Multi-channeling LC-MS research and forensic methods improves
efficiency and throughput
Multi-channeling also increases the cost-effectiveness of your
mass spectrometer
Acknowledgements
We thank Dr. Hashim Othman of BioReference Laboratories (Elmwood
e
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puts
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the other
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s varied
FIGURE 10. MS/MS & LC Conditions for EtG/EtS
Start data 0.1 min
Data window: 1.5 min
Total run time: 4.0 min
FIGURE 11. Typical results for EtG/EtS
Desired quantitation range from 100 to 5000 ng/mL achieved.
Bup/Norbup batches and EtG/EtS batches submitted to one or two
channels have throughputs of 15 or 28 injections per hour.
FIGURE 12. Multi-channeling Bup/Norbup & EtG/EtS Batches
Multi-channeling Bup/Norbup
across 2 channels while EtG/EtS
runs on one allows 26 Bup/Norbup
and 13 EtG/EtS injections/hour.
Using 2 channels for each does not
increase throughput but ensures
completion of all batches in case
one channel stops because of
leakage or over-pressurization.