3
Analyte
Start
Time
(min)
Stop
Time
(min)
Ionization
Mode
Precursor
Ion Mass
(
m/z
)
Product
Ion Mass
(
m/z
)
Collision
Energy
(V)
Tube
Lens
(V)
Levetiracetam
0.9
1.8
+
171.1
69.3
28
70
171.1
126.2
13
171.1
154.1
5
IS7
0.9
1.8
+
174.1
69.3
29
70
Theophylline
0.9
1.9
+
181.0
69.3
26
110
181.0
96.2
24
181.0
124.1
17
IS8
0.9
1.9
+
187.0
127.1
19
110
Felbamate
1.3
2.3
+
239.0
91.2
34
100
239.0
117.1
16
239.0
178.0
5
Rufinamide
1.3
2.3
+
239.0
127.1
23
100
239.0
211.0
5
239.0
222.0
11
IS5
1.3
2.3
+
243.0
182.1
5
100
Lacosamide
1.3
2.3
+
251.1
91.2
27
100
251.1
108.2
7
251.1
116.1
13
IS6
1.3
2.3
+
254.1
108.2
6
100
Carbamazepine diol
1.7
2.7
+
271.0
180.0
27
100
271.0
236.0
11
271.0
253.1
5
Carbamazepine-10,11-epoxide
1.9
2.8
+
253.0
180.1
29
100
253.0
210.0
13
253.0
236.0
12
10-hydroxycarbamazepine
1.9
2.9
+
255.0
179.0
36
100
255.0
194.0
19
255.0
237.0
5
IS3
1.9
2.9
+
259.0
198.0
19
100
IS2
1.9
2.9
+
263.1
190.1
25
100
IS4
2.4
3.4
+
257.0
184.0
25
100
257.0
212.0
19
257.0
240.0
13
Oxcarbazepine
2.5
3.5
+
253.0
180.0
25
100
253.0
208.0
19
253.0
236.0
11
Carbamazepine
2.9
3.9
+
237.0
165.0
42
100
237.0
179.1
32
237.0
194.0
19
IS1
2.9
3.9
+
247.1
204.1
20
100
Table 3. SRM settings – Group 1