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Thermo Scientific Poster Note
•
PN64314-EN 1114S
Conclusion
A method was developed for quantitative screening which can be used for
analysis of a virtually unlimited number of compounds in forensic toxicology.
Method linearity, precision and accuracy meet requirements for quantitative
screening in forensic toxicology laboratories.
Method is robust: limited matrix effects were observed.
Method can be multiplexed on dual channel LC system resulting in an
analytical time of less than 5 minutes.
00
350
400
450
333.1032
419.3143
7.0857 334.1065
441.2962
00
350
400
450
333.1033
334.1062
335.0992
4
413.0356
7.0756 336.1031
436.0518
AIF spectrum
223
224
225
7
225.0629
223.1181
2.1848
224.2001
225
s for selected
6-MAM 1 ng/mL
MDA 50 ng/mL
Norfentanyl 1 ng/mL
Zolpidem 1 ng/mL
FIGURE 3
.
Example of calibration curves and calibration standard accuracy tables
for selected compounds. Note: tolbutamide was used as internal standard for all
analytes.
All trademarks are the property of Thermo Fisher Scientific and its subsidiaries.
For Forensic Use Only. Not for use in diagnostic procedures.
This information is not intended to encourage use of these products in any manners that might infringe the
intellectual property rights of others.
Methylphenidate
1–1000 8.5
13.3 110–123
* Precision obtained for QC sample at concentration of 50 ng/mL