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AN63503 _E 11/11S
Table 1. Calibration ranges and method precision for all the analytes
Analyte
Calibration range Within-day Between-days
(ng/mL) (%RSD)* (%RSD) **
9-OH-Risperidone 5-500 7.1 5.5
Amisulpride 10-1000 3.9 3.4
Citalopram 5-500 4.9 5.1
Clozapine 10-1000 5.8 4.3
Desmethyl Sertraline 2-200 6.3 6.0
Fluoxetine 10-1000 3.4 3.4
Maprotiline 10-1000 4.2 4.1
Mianserine 5-500 6.2 5.1
Mirtazapine 2-200 5.9 4.4
Norclozapine 10-1000 5.9 3.6
Norfluoxetine 10-1000 6.5 5.0
O-Desmethyl-Venlafaxine 10-1000 4.3 4.8
Olanzapine 5-500 6.2 3.3
Paroxetine 5-500 6.2 5.3
Quetiapine 10-1000 5.2 3.5
Risperidone 1-100 5.8 5.4
Sertraline 2-200 4.5 3.4
Venlafaxine 10-1000 4.5 3.4
* Replicates analyzed each day = 10
** Days averaged = 10
Conclusion
A fast and analytically sensitive method for the detection
of 18 antidepressants and neuroleptics is described.
The Transcend TLX automated online sample
preparation system allows minimal sample preparation
and time saving in the absence of SPE sample preparation
for clinical research laboratories.
For Research Use Only. Not for use in diagnostic procedures.