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Introduction
Normal Phase Hydrophilic Phases
•
Polar-polar interactions
•
Dipole-dipole interactions
HyperSep Silica
A polar sorbent primarily used to retain analytes from
non-polar matrices
•
Surface area 530m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
Silica material is primarily used to extract analytes from non-polar
solvents such as hydrocarbons, less polar esters and ethers. Typical
application areas include extraction of aldehydes, amines, pesticides,
herbicides, carotenoids, fat soluble vitamins, aflatoxins, fatty acids
and phospholipids.
HyperSep Florisil
®
Ideal for the isolation of polar compounds from
non-polar matrices
•
Surface area 289m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
Florisil is a magnesia-loaded silica gel which has been specifically
designed for applications such as the extraction of pesticides using
AOAC and EPA methods, as well as polychlorinated biphenyls (PCBs)
in transformer oil.
HyperSep Aminopropyl
A polar sorbent for both polar and anion exchange interactions
•
Surface area 470 to 530m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
Aminopropyl is a silica-based material which can be used as both a
polar sorbent and a weak anion exchanger. Typical applications include
petroleum fractionation, saccharides, drugs and drug metabolites.
HyperSep Cyano
For retention of polar compounds from non-polar matrices
•
Surface area 470 to 530m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
Cyano is a silica-based material of low hydrophobicity. It is less retentive
than either silica or diol. Typical application areas include retention of
polar compounds from hexane and oil.
HyperSep Diol
For extraction of polar compounds
•
Surface area 470 to 530m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
A silica-based material which can be used for extraction of polar
compounds. Typical applications include normal phase extraction and
purification of polar compounds.
Ion Exchange Phases
•
Electrostatic interactions
HyperSep SAX (Strong Anion Exchanger)
Strong anion exchange sorbent for extraction of weak acids
•
Surface area 470 to 530m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
SAX is ideal for the extraction of negatively charged compounds from
both aqueous and non-aqueous matrices, as well as the extraction of
weak acids such as carboxylic acid. Typical application areas include
removal of acidic food pigments, removal of phenolic compounds,
nucleic acids and surfactants.
HyperSep SCX (Strong Cation Exchanger)
Strong cation exchange sorbent for extraction of charged basic
compounds
•
Surface area 470 to 530m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
SCX is ideal for the extraction of positively charged compounds from
both aqueous and non-aqueous matrices. Typical application areas
include extraction of antibiotics, drugs, organic bases, amino acids,
catecholamines and herbicides.
Mixed-Mode Phases
•
Two functional groups
•
Non-polar and ion exchange
•
Hydrophobic and ionic retention
•
Ideal for samples with complex structures
HyperSep Verify-CX
Non-polar and anionic characteristics for improved analysis of
basic drugs of abuse
•
Surface area 470 to 530m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
Verify-CX is a mixed-mode material based on two functional groups
bonded to the silica base: a reversed phase C8 group and a strong
cation exchanger. Typical application areas include the analysis of a
range of basic drugs of abuse from biological matrices.
HyperSep Verify-AX
Non-polar and cationic characteristics for improved analysis of
acidic drugs of abuse
•
Surface area 470 to 530m
2
/g
•
Particle size 40 to 60µm
•
Pore size 60Å
Verify-AX is a mixed-mode material based on two functional groups
bonded to the silica base: a reversed phase C8 group and a strong
anion exchanger. Typical application areas include the analysis of a
range of acidic drugs of abuse from biological matrices, including THC
and its metabolites.
Normal Phase
Silica Phases
Ion Exchange Phases