AI-64310-CRFT

Clinical Research Webinars

WB64304: Grow Your LC-MS Research and Forensic Lab Profitability with Cost-effective Analytical Workflows

This webinar presents LC-MS workflows for cost-effective research and forensic laboratory operation. The workflows,

enabled by simple sample preparation coupled with rapid analysis on a 4-channel multiplexing LC system, include

quantitation of vitamin D metabolites (25-OH-Vitamin D2 & D3) in blood serum and methylmalonic acid (MMA) in blood

serum for research use, buprenorphine and its metabolite norbuprenorphine in urine, and ethanol metabolites ethyl

glucuronide and ethyl sulfate (EtG/EtS) in urine for forensic use. High-throughput data quality and ease of operation

for reduced labor costs and consumables cost will be discussed.

WB64306: Exploring High Resolution Accurate Mass Orbitrap Technology for Comprehensive Urine Drug

Screening

Dr. Cristiana Stefan of CAMH will present the experience gained at her laboratory with comprehensive urine drug

screening for clinical research and forensic use. Using the Thermo Scientific™ Q Exactive™ hybrid quadrupole-

Orbitrap mass spectrometer, they were able to answer relevant questions for urine drug screening. Is this drug absent

or present in the urine? Are both parent and metabolites present, or only the metabolite(s)?

WB64308: Steroid Analysis using High Throughput Online Sample Clean-up and Easy to Use LC-MS System for

Research

This webinar presents a solution for high throughput robust LC-MS analysis of biological specimens. Conventionally

considered complex, online sample matrix removal and chromatography multiplexing are provided with easy to use

and maintenance free LC design for technician work. The cost efficient methods and system simplicity help to make

the lab more profitable. The instrument performance will be demonstrated using analysis of Testosterone in plasma and

analysis of Cortisol in urine.