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Conclusion
A highly sensitive, accurate and robust SRM-based approach
for PFC analysis was developed on a PFC-free Accela-TSQ
Vantage LC-MS platform. PFCs were accurately and
reproducibly detected at ppt levels in neat solution and
in human milk. The unique H-SRM capability of the
TSQ Vantage instrument removed interference peaks and
significantly improved selectivity. Furthermore, unlike
other approaches, this platform does not require trapping
or column switching techniques to ensure exceptional
sensitivity in high chemical backgrounds.
References
1.
http://www.epa.gov/oppt/pfoa/2.
http://www.epa.gov/heasd/regulatory/projects/d1b_right_to_know.html3. Tao, L.; Kannan, K.; Wong, C.M.; Arcaro, K. F.; Butenhoff, J.L.
Perfluorinated compounds in human milk from Massachusetts, U.S.A.
Environ Sci Technol
.
2008
42
, 3096-101.