Application Note 52295
Conclusion
The ISQ
™
single quadrupole GC-MS system utilizing the
TriPlus
™
RSH autosampler and a PTV inlet (CT-Splitless
mode) demonstrated its capability to analyze 1,4-dioxane
according to EPA Method 522. It easily met the criteria
for tuning with BFB and for calibration down to a level of
0.05 ppb. For better accuracy at the lower end of the
curve, 1/x weighting was used to meet all of the criteria of
the initial calibration of EPA Method 522. SIM analysis
gave excellent results at low concentrations. The added
advantage of the SIM/Full Scan mode is the ability to
identify unknowns with a NIST or other library, while
producing accurate results for 1,4-dioxane.
References
1) International Chemical Safety Card: 1,4-Dioxane.
National Institute for Occupational Safety and Health.
.
Retrieved 15 May 2012.
2)http://www.organicconsumers.org/bodycare/
DioxaneRelease08.cfm
3) “1, 4-Dioxane Fact Sheet: Support Document”. OPPT
Chemical Fact Sheets. United States Environmental
Protection Agency. February
1995
.
4)EPA/600/R-08/101, Method 522 Determination of
1,4-Dioxane in Drinking Water by Solid Phase
Extraction (SPE) and Gas Chromatography/Mass
Spectrometry (GC/MS) with Selected Ion Monitoring
(SIM), Version 1.0, September,
2008
, Jean W. Munch
and Paul E. Grimmett.
AN52295_E 06/12S
Africa-Other
+27 11 570 1840
Australia
+61 3 9757 4300
Austria
+43 1 333 50 34 0
Belgium
+32 53 73 42 41
Canada
+1 800 530 8447
China
+86 10 8419 3588
Denmark
+45 70 23 62 60
Europe-Other
+43 1 333 50 34 0
Finland/Norway/Sweden
+46 8 556 468 00
France
+33 1 60 92 48 00
Germany
+49 6103 408 1014
India
+91 22 6742 9434
Italy
+39 02 950 591
Japan
+81 45 453 9100
Latin America
+1 561 688 8700
Middle East
+43 1 333 50 34 0
Netherlands
+31 76 579 55 55
New Zealand
+64 9 980 6700
Russia/CIS
+43 1 333 50 34 0
South Africa
+27 11 570 1840
Spain
+34 914 845 965
Switzerland
+41 61 716 77 00
UK
+44 1442 233555
USA
+1 800 532 4752
©2012 Thermo Fisher Scientific Inc. All rights reserved. Siltek is a registered trademark of SilcoTek Corporation. ISO is a
trademark of the International Standards Organization. All other trademarks are the property of Thermo Fisher Scientific Inc.
and its subsidiaries. This information is presented as an example of the capabilities of Thermo Fisher Scientific Inc. products. It
is not intended to encourage use of these products in any manners that might infringe the intellectual property rights of others.
Specifications, terms and pricing are subject to change. Not all products are available in all countries. Please consult your local
sales representative for details.
Thermo Fisher
Scientific,Austin,TX
USA is ISO Certified.
