TN20641_E 10/12S
Technical Note 20641
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Figure 4: Performance comparison of Accucore XL 4 µm HPLC column and fully porous 5 µm and 3 µm columns using kinetic plots:
column impedance (E) relative to linear velocity (u). All columns: 150 x 4.6 mm; test conditions: water / acetonitrile (50:50 v/v); column
temperature: 30 °C; test probes: o-xylene and theophylline (t
0
marker)
Conclusion
• The Accucore XL 4 µm solid core HPLC columns
provide improvements in efficiency in excess of 50%
over fully porous 5 μm and 3 µm columns.
• The backpressure of the Accucore XL 4 µm solid core
HPLC column is 42% higher than fully porous 5 µm,
but 13% lower than fully porous 3 µm.
• The Accucore XL 4 µm solid core HPLC columns
exhibit significantly lower impedance than fully
porous materials.
Impedance
u
0
(mm/s)
1.E+03
1.E+04
1.E+05
0
10
1
Accucore XL 4
µ
m
Fully porous 5
µ
m
Fully porous 3
µ
m