Figure 3: Performance comparison of Accucore and competitor solid core columns using kinetic plots: column impedance (E) relative to
linear velocity (u). All columns: 100 x 2.1 mm; test conditions: mobile phase water / acetonitrile (50:50 v/v), column temperature:
30 °C, test probes: o-xylene and theophylline (t
0
marker).
Impedance - E
Linear Velocity - u
0
(mm/s)
1.E+03
1.E+04
Accucore RP-MS 2.6
µ
m
Nucleoshell RP-C18 2.7
µ
m
Poroshell 120 SB-C18 2.7
µ
m
Halo C18 2.7
µ
m
Kinetex C18 2.6
µ
m
Ascentic Express C18 2.7
µ
m
Sunshell C18 2.6
µ
m
1
50
5
TN20640_E 10/12S
Technical Note 20640
© 2012 Thermo Fisher Scientific Inc. All rights reserved. Ascentis
®
is a registered trademark of Sigma-Aldrich Co. Halo
is a registered trademark of Advanced
Materials Technologies Inc. Kinetex
is a registered trademark of Phenomenex Inc. Nucleoshell is a registered trademark of MACHEREY-NAGEL GmbH & Co.
Poroshell
is a registered trademark of Agilent Technologies Inc. SunShell
is a registered trademark of ChromaNik Technologies Inc., Japan. Agilent is a registered
trademark of Agilent Technologies Inc. All other trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries. This information is presented as
an example of the capabilities of Thermo Fisher Scientific Inc. products. It is not intended to encourage use of these products in any manners that might infringe
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your local sales representative for details.
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Conclusion
• Accucore HPLC columns generate a lower
backpressure than the majority of solid core
competitors.
• Accucore HPLC columns generate higher efficiencies
than all solid core competitors.
• Accucore HPLC columns generate lower impedances
than all solid core competitors.
References
[1] G. Desmet, P. Gzil, D. Clicq, LC GC Europe,
18 (2005) 403
[2] Hans Poppe, J. Chromatogr. A, 778 (1997) 3
The data is a mixture of averages and representative data points,
but is always consistent from column to column.
Testing was performed by members of our Applications R&D
team.
Comparative performance may not be representative of all
applications.
Purchasers must determine the suitability of products for their
particular use.