Page 130 - CRFTApplication Compendium_090613
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Conclusion
• The method was easy to set up. No compound tuning
was required.
• The method showed good linearity across the
calibration ranges.
• Controls indicated good method precision
and robustness.
• The Exactive Plus MS produced results comparable to a
triple-stage quadrupole method, showing the suitability
of Orbitrap technology for routine quantitation of
whole blood samples by clinical research laboratories.
Acknowledgement
The authors would like to thank Dr. William Clarke of
Johns Hopkins Medical Institute for his valuable insights
and discussions.
Reference
1. Thermo Scientific ClinSpec Immunosuppressants Test
product insert.
For Research Use Only. Not for use in diagnostic procedures.
AN63667_E 01/13S
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