Table of Contents
(Click on the App Note number to view.)
Endocrine Analysis for Clinical Research
Fast and Sensitive LC-APCI-MS/MS Quantitative
Analysis of Estrone and Estradiol in Serum without
Chemical Derivatization. Page 3
Quantitative LC-MS/MS Analysis of 25-OH Vitamin
D3/D2 Comparing 1D Chromatography, 2D Chromatography
and Automated Online Sample Preparation . Page 9
Quantitative Analysis of 1,25-dihydroxyvitamin
D2 and D3 using Immunoaffnity Extraction with
APCI-LC-MS/MS. Page 13
Quantitative Determination of Testosterone in
Plasma Using Unique Automated Online Sample Preparation
and LC-MS/MS . Page 15
Selective Testosterone Analysis in Human Serum
by LC-FAIMS-MS/MS. Page 17
Quantitative Analysis of Testosterone in Serum
by LC-MS/MS . Page 23
uantitative Analysis of Cortisol and Cortisone
in Urine by LC-MS/MS. Page 27
Therapeutic Drug Analysis for Clinical Research
Simultaneous Quantitative Analysis of Four
Immunosuppressive Drugs Using High Resolution Accurate
Mass LC-MS . Page 31
Validated LC-MS/MS Method for the Analysis
of Immunosuppressant Drugs in Whole Blood Using the
RECIPE ClinMass
®
Complete Kit . Page 35
Quantitative Analysis of Mevalonate in Plasma
Using LC-MS/MS. Page 37
Quantitative Analysis of Immunosuppressant
Drugs in Whole Blood Using High Throughput
LC-MS/MS. Page 39
Research Analysis of Clozapine and Norclozapine
in Plasma Using Automated Sample Preparation and
LC-MS/MS. Page 41
Bioanalytical Assay for Neurotransmitters
in Whole Blood by LC-MS/MS. Page 45
Determination of Digoxin in Serum by Liquid
Chromatography–Tandem Mass Spectrometry. Page 49
Improved Quantitative Selectivity of Clenbuterol in
Human Urine Using High Resolution on the TSQ Quantum
Mass Spectrometer . Page 53
Drugs of Abuse and Pain Management
Drug Analysis for Forensic Toxicology
Targeted Screening of Drugs of Abuse and Toxic
Compounds with LC-MS/MS Using Triple Stage
Quadrupole Technology. Page 57
Quantitative LC-MS Analysis of 14 Benzodiazepines
in Urine Using TraceFinder 1.1 Software and High Resolution
Accurate Mass. Page 61
Screening of 20 Benzodiazepines and Four Metabolites
in Whole Blood using UHPLC-MS/MS . Page 69
A Fully Automated LC-MS Screening System
using Automated Online Sample Preparation for Forensic
Toxicology . Page 71
Screening for Drugs and Toxic Compounds:
Comparison between lc-ms/ms, hplc-dad, and
Immunoassay. Page 73
Screening and Quantifcation of Multiple Drugs
in Urine Using Automated Online Sample Preparation
and Tandem Mass Spectrometry . Page 77
Forensic Toxicology Screening with LC-MS/MS
and Automated Online Sample Preparation . Page 79
Quantitative LC-MS Screening for Illicit Drugs
Using Ultrahigh Resolution Mass Analysis and Accurate
Mass Confrmation. Page 81
Screening in Equine Doping Control Analysis
with Ultrahigh Resolution and Accurate Mass. Page 83
Quantitation of 12 Benzodiazepines and Metabolites
in Urine Using Ultrahigh Resolution LC-MS for Forensic
Toxicology Use. Page 87
Quantitation of Urinary Ethyl Glucuronide
and Ethyl Sulfate Using Ultrahigh Resolution. Page 89
Simultaneous Analysis of Opiates and
Benzodiazepines in Urine in Under 3 Minutes per
Sample Using LC-MS/MS. . . . . . . . . . . . . . . . . . . . . . . . . Page 91
Screening Drugs and Toxic Compounds with
LC-MS/MS: An Alternative to LC-UV for Research
Toxicology Labs. Page 93
Forensic Analysis of Opiates in Whole
Blood by LC-MS/MS Using Automated, Online
Sample Preparation . Page 97
Rapid Analysis of Opiates from Low Volume
Whole Blood Samples by LC-MS/MS Utilizing
TurboFlow Methods. Page 99
Quantitation of Fentanyl and Norfentanyl from
Urine Using On-line High Throughput System. Page 103
A Complete Toxicology Screening Procedure
for Drugs and Toxic Compounds in Urine and Plasma
Using LC-MS/MS. Page 105
UHPLC/MS: An Effcient Tool for Determination
of Illicit Drugs . Page 113
Improved Signal-to-Noise Ratio in the
Antidoping Analysis of Clenbuterol in Urine Using
LC–FAIMS–H-SRM. Page 119
A Quantitative Test for Multiple Classes of Illicit
Drugs and Their Primary Metabolites in Human Biological
Fluids by LC-MS/MS for Forensic Use . Page 123
Determination of LSD and Its Metabolites in
Human Biological Samples by Liquid Chromatography–
Tandem Mass Spectrometry. Page 127
nalysis of Multiple Illicit Drugs, Methadone,
and their Metabolites in Oral Fluid Using a Linear Ion
Trap Mass Spectrometer . Page 131
Rapid Quantitative and Confrmational
Screening for Drugs in Race Horse Urine by
ESI-LC-MS/MS and MS
3
. Page 135
MS/MS as an LC Detector for the Screening
of Drugs and Their Metabolites in Race Horse Urine. Page 143